National Poisons Information Service

A service commissioned by Public Health England




Members of the public

seeking specific

information on poisons

should contact:


In England and Wales:

NHS 111 - dial 111


In Scotland:

NHS 24 - dial 111


In N Ireland:

Contact your local GP or

pharmacist during

normal hours; click here

(www.gpoutofhours for GP

services Out-of-Hours.


In Republic of Ireland:

01 809 2166



professionals seeking

poisons information

should consult:



TOXBASE is the primary clinical toxicology database of the NPIS. It is the backbone of the service and the first-line resource for UK healthcare professionals.


Please note that if the TOXBASE website is not working please try the backup site:


Hospitals, general practitioners and other health care workers in the UK have direct access to TOXBASE, the clinical toxicology database which is specifically designed for healthcare professionals. TOXBASE is coordinated by the NPIS (Edinburgh Unit), with input from all four NPIS Units. Doctors should consult TOXBASE before telephoning for more expert and specific advice.


All NPIS Units contribute to and authenticate the content of TOXBASE and it represents the most authoritative source of information available. It should be used by all medical practitioners and other health care professionals working in the NHS as the primary source of poisons information. One of NPIS's major tasks is to ensure this key resource remains up-to-date and relevant. This is a considerable undertaking, requiring up to 5,000 product entries to be written or revised every year.


Accesses to its database have increased steadily since 1999. Now, on average, more than 1.8 million accesses are made every year - or one every minute. Each year more than half a million users log onto the site and the great majority are accident and emergency hospital staff.


The TOXBASE database provides information about routine diagnosis, treatment and management of patients suffering from exposure to a wide range of pharmaceuticals, chemicals (agricultural, household and industrial), plants and animals.  The database includes information on about 17,200 entries together with information on poisoning in pregnancy, harmful chemicals, chemical incidents, antidotes, antivenoms and educational activities.  Information boxes are available for NHS 111 and NHS 24 nurse advisers to enable them to decide on the correct disposition for their callers.  News alerts and newsletter updates are also included. 


TOXBASE is available free to UK National Health Service registered users who will normally be departments or surgeries, rather than individuals.  Hospitals and NHS 111 and NHS 24 centres are the major users of the database. There are around 5000 active users, mainly in the UK and Northern Ireland.  TOXBASE is not intended for personal use of UK NHS staff, although group training passwords are available for medical schools and for some other appropriate courses. 


Suitable commercial users are charged an annual subscription, and overseas and other non-NHS users may be allowed access by negotiation, subject to UK Health Protection Agency approval. TOXBASE is not available for public access.  


To register for TOXBASE please submit an on-line registration form at


Substances listed alphabetically include pharmaceuticals, drugs of abuse, cosmetics, toiletries, household products, industrial chemicals, agrochemicals, snakes, insects and plants. It is updated on a regular basis.


Click for information on the TOXBASE users update and TOXBASE technical information and e-learning site.


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