Highlights from the 2014 NPIS Annual Report - 2,4-dinitrophenol
In 2014 the NPIS reported a steep rise in telephone enquiries and TOXBASE user sessions relating to 2,4-dinitrophenol (DNP), a synthetic industrial chemical. Although not licensed as a medicine, some websites promote DNP as a supplement for weight loss and 'fat burning'. These increases in enquiry numbers, which occurred in spite of warnings made by the Food Standards Agency in November 2012, were of concern becuase of the severe toxicity that DNP can cause, especially with higher doses.
National Poisons Information Service
The National Poisons Information Service (NPIS) is the UK Departments of Health approved, and Public Health England commissioned, national service that provides expert advice on all aspects of acute and chronic poisoning.
The role of the National Poisons Information Service (NPIS) is to reduce the burden of healthcare associated with poisoning by the provision of rapidly available, consistent and evidence-based advice to front-line NHS healthcare professionals. The purpose of this advice is to facilitate optimal clinical management of patients with confirmed or suspected poisoning and those who are (or may be) exposed to medicines or other potential poisons during pregnancy. Where toxicity is low, NPIS offers advice to minimise unnecessary hospital attendances and admissions.
The service comprises four individual Units, based in Birmingham, Cardiff, Edinburgh and Newcastle. Each Unit is staffed by Consultant Clinical Toxicologists and Specialists in Poisons Information who work together to provide a seamless national service that has been established for 50 years.
The National Poisons Information Service is the service to which frontline NHS staff turn for advice on the diagnosis, treatment and care of patients who have been - or may have been - poisoned, either by accident or intentionally.
NPIS is funded mainly through ‘Government Grant in Aid’ from the UK Health Departments, some contract income and some research income.